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Mechanisms
of Cardiovascular Development
 The area offers training and research in genetics and developmental biology, with investigators utilizing a variety of animal models to assess gene functions in embryonic development. Modern developmental genetics has become a central organizing field in all traditional disciples of biology, including cell biology, molecular biology, anatomy, evolution, and ecology. It has also contributed greatly to more practical fields such as medicine, environmental science and agriculture. The model systems studied by faculty members include Drosophila (fruit fly) for vascular system development, zebrafish for cardiac function and environmental impact on embryogenesis, chick for the formation of the cardiovascular system, mice for a variety of organogenesis studies, hematopoiesis, heart morphogenesis and human familial diseases for genetic linkage studies. In addition to transgenic and knockout technology, a variety of cell culture systems, including those for human stem cells, are utilized in the research. |
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| Christopher
Drake, Ph.D. |
Vasculogenesis |
| Carol
A. Eisenberg, Ph.D. |
Phenotypic Potential of Adult Tissue-derived Stem Cells |
| Leonard Eisenberg, Ph.D. |
Regulation of Stem Cell Potential and Cardiac Induction |
| Robert
G. Gourdie, Ph.D. |
Developmental and Molecular Biology of Cardiac Conduction Wound Healing |
| Brett Harris, Ph.D. |
The Development of the Atrio-ventricular Conduction System |
| Amanda LaRue, Ph.D. |
Hematopoietic Stem Cells in the Development and Progression of Solid Tumors |
| Kyo
Ho Lee, M.D., Ph.D. |
Transcriptional Regulation in Cardiac Development |
| Edward
L. Krug, Ph.D. |
Assessing the Anatomical Proteome of Heart Morphogenesis |
| Steven
W. Kubalak, Ph.D. |
Signaling Mechanisms Regulating Cardiac Remodeling |
| Roger
R. Markwald, Ph.D. |
Developmental Basis of Cardiovascular Disease |
| Vladimir
Mironov, M.D., Ph.D. |
Cardiovascular Tissue Engineering and Cardiovascular Regenerative Medicine |
| Terrence
O'Brien, M.D. |
Transcriptional Regulation of Specified Genes Involved in Cardiac Hypertrophy and the Development of the Conduction System |
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| Robert
P. Thompson, Ph.D. |
Regulation of Myocyte Proliferation in Heart Development |
| Arno
Wessels, Ph.D. |
Mechanisms of Cardiac Morphogenesis |
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©2003 MUSC |
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