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Proteomics
 The Cardiovascular Proteomics group provides trainees exposure to new technologies for proteomic analysis and helps our fellows apply such approaches to generate discoveries in specific areas of cardiovascular research. Our faculty are using proteomic analysis to study the basic underlying mechanisms of congestive heart failure, extracellular matrix remodeling events in heart development and disease, proteomic analysis of cardiovascular disease risk and several new technologies for proteomic assessment of heart disease. One of our current trainees is developing proteomic methods to study diastolic dysfunction. Work on his and other projects is being initiated using a synergistic combination of contemporary two-dimensional gel electrophoresis in a new high throughput facility, a well-established mass spectrometry facility, and state-of-the-art methods of biological systems analysis. |
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| Scott
W. Argraves, Ph.D. |
Extracellular
Matrix Biology |
| John
M. Arthur, M.D., Ph.D. |
Discovery of Disease Biomarkers Using Proteomic and Informatic Technologies |
| John
Baatz, Ph.D. |
Characterization
of Hemoglobin and Surfactant Protein in Distal Airway Cells |
| Daniel
Knapp, Ph.D. |
Proteomic Analysis Using Mass Spectrometry Approaches |
| Edward
Krug, Ph.D. |
Assessing the Anatomical Proteome of Heart Morphogenesis |
| Roger
R. Markwald, Ph.D. |
Developmental Basis of Cardiovascular Disease |
| Kevin
L. Schey, Ph.D. |
Proteomics and Protein Structure |
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| Francis
G. Spinale, M.D., Ph.D. |
Cellular Mechanisms of Heart Failure |
| Michael
R. Zile, M.D. |
Diastolic Heart Failure and Growth Regulation |
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©2003 MUSC |
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